The ribosome serves as the essential molecular machine that translates genetic information carried by messenger RNA (mRNA) into functional proteins. Comprised of two distinct subunits, the ribosome ...

Understanding the best ways to get a membrane protein to its destination in a cell is crucial, and the best method to make this happen is still unclear. Cell-free systems allow for interactions ...

A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER). Inspired by natural mechanisms found in ...

This film creatively illustrates the process of protein synthesis through dance, symbolizing the assembly of amino acids into proteins. It explains how genes encode instructions for amino acid ...

The discovery of ribosomes dates back to the 1950s, when George Palade first observed dense particles in the cytoplasm of cells using electron microscopy. These particles were later named "ribosomes" ...

tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...