Researchers found that sperm RNA profiles shift with paternal age in both mice and humans. Using PANDORA-seq, they identified ...
circRNA, circular RNA; dsRNA, double-stranded RNA; lncRNA, long non-coding RNA; mRNA, messenger RNA; miRNA, microRNA; ncRNA, non-coding RNA; pre-miRNA, precursor miRNA; pri-miRNA, primary miRNA; RISC, ...
Hidden RNA signals in sperm reveal an "aging cliff" that could impact offspring health.
A new study now suggests that the answer may lie not just in DNA, but in a lesser-known molecular messenger carried by sperm: RNA. RNA plays a critical role in regulating how genes are switched on and ...
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Sperm RNA aging shift that may explain paternal age effects
By Dr. Priyom Bose, Ph.D. A newly revealed “aging cliff” in sperm RNA marks a conserved molecular transition from youth to ...
A new review highlights the transformative potential of transfer RNA-derived small RNAs (tsRNAs) in the field of liquid biopsy, emphasizing their role as promising biomarkers for a wide range of ...
An interdisciplinary and international research group led by Dr. Volker Busskamp from the Center for Regenerative Therapies Dresden at the TU Dresden (CRTD) has decoded the regulatory impact on ...
What are Micro-RNAs (miRNAs)? Micro-RNAs (miRNAs) are a class of small, non-coding RNA molecules that play a crucial role in regulating gene expression at the post-transcriptional level. These tiny ...
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