The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

Skeletal muscle can be functionally compromised by genetic myopathies, aging, traumatic injuries and tumor ablation. Under some conditions, such as severe traumatic injuries and volumetric muscle loss ...

Researchers have provided an in-depth analysis of 3D in vitro biomimetic skeletal muscle tissue models, highlighting the great potential of bioprinting technology. Skeletal muscle can be functionally ...

Scientists are using in vitro skeletal muscle engineering to gain a better understanding of the complex genetic and environmental factors underlying diabetes, putting lab-grown, healthy skeletal ...

“This article illuminates the biology behind EDG-5506, demonstrating that modulation of fast skeletal muscle contraction protects against muscle injury, degeneration and fibrosis in models of DMD,” ...

Researchers analyzed DNA methylation in human skeletal muscle and identified age-linked epigenetic markers that enable highly ...

A model combing an immune-related genes signature and an extracellular matrix-related genes signature in predicting prognosis of left- and right-sided colon cancer. Genetic variants involved in the ...