Signal transduction is the fundamental process by which cells convert external cues into tailored intracellular responses. Through a cascade of molecular events—beginning at the cell membrane with the ...

DEATH DUEL: One TNF receptor 1 pathway activates apoptosis, another triggers gene expression-roles in seeming opposition, says David Goeddel. H. Hsu, H Shu, M. Pan, D.V. Goeddel, "TRADD-TRAF2 and ...

STRESSED OUT: Jöel Raingeaud, left, and Roger Davis found that the p38 MAP kinase is activated by inflammatory cytokines and environmental stress. J. Raingeaud, S. Gupta, J.S. Rogers, M. Dickens, J.