准确预测免疫毒性对化学安全和药物开发至关重要,本研究通过可解释的QSAR模型结合三种人免疫细胞(Jurkat、PBMC、THP-1)的IC50数据,采用树模型算法和特征选择技术识别关键分子结构,利用SHAP方法增强模型可解释性,揭示了免疫毒性机制并验证了整合细胞特异 ...
Cooperative game theory is the study of strategic interactions in which players, or agents, form coalitions to achieve mutual benefits. A central concern in this area is the fair allocation of the ...
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