The study of experimental evolution in Escherichia coli has provided unprecedented insights into the mechanisms of adaptive mutations, elucidating how populations diverge and optimise their fitness ...
Researchers published a new study, “Ongoing chromothripsis underpins osteosarcoma genome complexity and clonal evolution,” in Cell that they say solves the mystery of what drives the genomic ...
For a long time, evolutionary biologists have thought that the genetic mutations that drive the evolution of genes and proteins are largely neutral: they're neither good nor bad, but just ordinary ...
Researchers at Scripps have created T7-ORACLE, a powerful new tool that speeds up evolution, allowing scientists to design and improve proteins thousands of times faster than nature. Using engineered ...
Biologists are closing in on a puzzle that seems to turn classic evolutionary logic inside out, yet may be so common that it deserves to be called a new rule of life. Instead of always purging harmful ...
A groundbreaking study published in this week’s issue of PNAS by scientists from Israel and Ghana shows that an evolutionarily significant mutation in the human APOL1 gene arises not randomly but more ...
This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...
A new study by researchers at the Max Planck Institute for Evolutionary Biology (MPI-EB) sheds fresh light on one of the most debated concepts in biology: evolvability. The work provides the first ...