Mitochondria are essential organelles that drive energy production, regulate apoptosis and orchestrate metabolic signalling within cells. Their dynamic nature underpins processes as diverse as ATP ...

Cirrhotic cardiomyopathy (CCM) is a significant complication of cirrhosis, but its progression and underlying mechanisms ...

Prof. Ciro Leonardo Pierri's expertise in structural biology, mitochondrial carrier modeling, and drug targeting—demonstrated ...

Mitochondrial dysfunction is associated with various chronic diseases and cancers, including neurodegenerative diseases and ...

Area of Focus: mitochondrial quality control, cellular metabolism, immune responses and the mechanisms underlying neurodegenerative diseases. Fourteen years ago, Xin Qi joined the Department of ...

Pretzel Therapeutics is advancing its mitochondrial disease therapies, pushing lead candidate PX578 through Phase 1 trials ...

Reduction in mitochondrial activity in multiple sclerosis contributes to Purkinje cell loss. Researchers at the University of California, Riverside (CA, USA) have demonstrated the role mitochondrial ...

While Alzheimer's Disease is traditionally associated with the buildup of plaques, emerging evidence suggests that mitochondrial dysfunction may play a role in the onset and progression of this ...

Stealth BioTherapeutics Inc. (the "Company" or "Stealth"), a commercial-stage biotechnology company focused on the discovery, development and commercialization of novel therapies for diseases ...

Mitochondrial respiratory complexes (Complexes I–V) and their assembly into respiratory supercomplexes (SCs) are fundamental to liver bioenergetics, redox homeostasis, and metabolic adaptability.