At the onset of diabetic cardiomyopathy, Trdn-as expression increases, which regulates the methylation of Casq2 mRNA mediated by METTL14, thus increasing the stability and expression of Casq2 mRNA.

Long noncoding RNAs (lncRNAs) play diverse roles in biological processes, but their expression profiles and functions in cervical carcinogenesis remain unknown. By RNA-sequencing (RNA-seq) analyses of ...

A sum of 921 samples were collected from three independent data sets. We obtained pyroptosis-related genes from both the Molecular Signatures Database and relevant literature sources and used four ...

When a gene produces too much protein, it can have devastating consequences on brain development and function. Patients with an overproduction of protein from the chromodomain helicase DNA binding ...

Identification of Pancreatic Cancer Germline Risk Variants With Effects That Are Modified by Smoking A sum of 921 samples were collected from three independent data sets. We obtained ...

A study in mouse models and human tissue, carried out by researchers at the Barcelona Institute of Science and Technology Centre for Genomic Regulation (CRG), has found that the small nuceleolar RNA ...

Scientists at the University of Pittsburgh, together with colleagues at the University of Pittsburgh School of Medicine and University of Pittsburgh Cancer Institute, have identified how a long ...

The Rinn Lab examines the mechanisms through which the class of functional RNAs known as long noncoding RNAs (lncRNAs) regulate essential biological processes. Thousands of lncRNAs exist, but only a ...

Crystal structure of the NHL domain of mouse TRIM71 complexed with a stem-loop structured Trincr1 RNA motif. Detailed interactions between key residues of TRIM71 and Trincr1 RNA are shown in an ...

As key players of gene regulation in many bacteria, small regulatory RNAs (sRNAs) associated with the RNA chaperone Hfq shape numerous phenotypic traits, including metabolism, stress response and ...