Nuclear speckles are non–membrane-bound organelles known as storage sites for messenger RNA (mRNA) processing and splicing factors. More recently, nuclear speckles have also been implicated in ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, No. 32 (August 10, 2021), pp. 1-11 (11 pages) Family with sequence similarity 20C (Fam20C), the major protein ...

The protein kinase CK2 is involved in a wide range of biological processes and cellular functions, including inflammatory responses and pathologies associated with inflammation. Also, its aberrant ...

(MEMPHIS, Tenn. – December 18, 2025) Scientists at St. Jude Children’s Research Hospital have characterized a hidden intermediate state at the center of Src kinase function. This hidden state allows ...

Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center of Src kinase function. This hidden state allows the kinase to repeatedly modify its ...

Phosphorylation involving serine-threonine kinases is a pervasive form of biological regulation found across the tree of life. To assault bacteria in a new way, O'Boyle and colleagues suggest acting ...

Inhibition of the COQ8 protein could be beneficial in the treatment of diseases such as cancer. COQ8 is needed for the biosynthesis of coenzyme Q, also known as ubiquinone. A new collaborative study ...