Cystic fibrosis is an inherited illness that can be screened for during pregnancy. The test determines whether you have any altered genes that you can pass on to your child. Having the information can ...

After a breast-cancer diagnosis and a separate scare, my mom tested for the BRCA2 gene mutation. Knowing it could be hereditary, I decided to get tested at 23 to see if I also carried the mutation. My ...

Gila Pfeffer is a humor writer who splits her time between NYC and London. The following is an adapted excerpt from her memoir, "Nearly Departed: Adventures in Loss, Cancer, and Other Inconveniences." ...

Population-level identification of patients with MMR mutation-positive endometrial cancer is optimized by stepwise testing for tumor MMR IHC loss in patients younger than 60 years, tumor MLH1 ...

Both breast and ovarian cancer risk is influenced by a variety of factors, including age, family history, lifestyle, and more. Variations in two specific genes, BRCA1 and BRCA2, also influence the ...

Real-world analyses of major adverse cardiovascular event risk by drug class after initiation of androgen deprivation therapy. Evaluation of compliance of next-generation sequencing (NGS) testing in ...

The general population has less than a 20 percent chance of developing breast cancer. However, for a person who tests positive for a gene mutation linked to breast cancer, the risk goes up to 87 ...

The Pig-A gene plays a pivotal role in the biosynthesis of glycosylphosphatidylinositol (GPI) anchors, which tether a multitude of proteins to the cell surface. Mutations in this X‐linked gene result ...

A new "proteomic" blood test can accurately screen a newborn's DNA for thousands of rare, inherited diseases by analyzing just a single-milliliter sample, according to a study to be presented Monday.

The assessment compared tumour testing strategies involving microsatellite instability (MSI) testing, immunohistochemistry (IHC) testing (both with and without further testing to exclude sporadic ...

Credit: Getty Images Determining the presence or absence of gene mutations associated with aggressive prostate cancer can have implications for risk stratification, monitoring, and therapy. Genetic ...