During the process of phagocytosis, polymorphonuclear leukocytes (PMN) release lysosomal enzymes into the extracellular medium. When the antibiotic cytochalasin B (CB) is present in the incubation ...

Sanofi has developed a simpler way to create site-specific antibody-to-mannose-6-phosphate (M6P) conjugates that eliminates the need for enzyme remodeling. This more straightforward method makes M6P ...

This method uses polymer modifications to tune enzyme activity for increased solubility in non-native solvents. Tuning the miscibility of enzymes in non-native solvent environments has important ...

Archaeosine is synthesized via three steps in tRNA. ArcS, the second-step enzyme, transfers a lysine to preQ 0, which is introduced into tRNA by ArcTGT, the first-step enzyme. The resultant preQ 0-Lys ...

Proteins are the workers in a cell and, as the "basic element of life", are responsible for the most widely varying metabolic processes. In plants, for example, they take on an important function in ...

Whether they are laundry detergents, mascara, or Christmas chocolate, many everyday products contain fatty acids from palm ...

Itaconate, an endogenous mitochondrial metabolite produced by the enzyme aconitate decarboxylase 1 (ACOD1), has emerged as a central regulator of ...

A team has modeled improving photosynthesis through enzyme modification and simulated soybean growth with realistic climate conditions, determining to what extent the improvements in photosynthesis ...

STORM Therapeutics Ltd. (STORM), the clinical stage company pioneering cellular reprogramming through RNA modifications to treat disease, today announced a strategic collaboration with Alida ...

This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...