单次高剂量EPO注射通过上调骨髓M-CSF水平及CD115表达,促进破骨细胞前体增殖,导致小鼠骨体积显著减少,并伴随骨形成标志物P1NP下降和骨吸收标志物TRAP5b升高,揭示EPO可能通过M-CSF通路引发早期骨稳态失衡。 Erythropoietin (EPO) is a hormone primarily known for its role in ...
To elucidate the safety and efficacy of exogenous erythropoietin (EPO) for the protection of photoreceptor cells in a rat model of retinal detachment (RD). Intravitreal injection of EPO 400 ng into ...
Recombinant human erythropoietin (EPO) improves cognitive performance in neuropsychiatric diseases ranging from schizophrenia and multiple sclerosis to major depression and bipolar disease. This ...