编者按:今年以来,siRNA疗法在治疗凝血相关疾病的研究方面取得了重要里程碑进展。RNA干扰(RNAi)机制通过在肝脏细胞中沉默编码凝血因子或天然抗凝物的mRNA,为治疗凝血相关疾病提供了一种全新的治疗模式。基于GalNAc偶联的递送技术,是将治疗性siRNA分子高效递送到肝脏的关键之一。药明康德旗下WuXi ...
Superwarfarins represent a class of long‐acting anticoagulant rodenticides that exert their effect through profound inhibition of vitamin K recycling, primarily by targeting vitamin K epoxide ...
For men with hemophilia B, receipt of gene therapy comprising an infusion of etranacogene dezaparvovec results in sustained endogenous factor IX expression and low annualized bleeding rates over five ...
NEW YORK, Jan. 16, 2025 /PRNewswire/ -- Report on how AI is driving market transformation - The global heparin market size is estimated to grow by USD 3.34 billion from 2024-2028, according to ...
For men with hemophilia B, receipt of gene therapy comprising an infusion of etranacogene dezaparvovec results in sustained endogenous factor IX expression and low annualized bleeding rates over five ...
To help diagnose von Willebrand disease or other bleeding disorders, a doctor will request various blood tests. These tests will measure the presence and activity of certain substances in the blood.
Researchers at McMaster University have made a groundbreaking discovery in the field of hematology, providing an explanation for spontaneous and unusual blood-clotting that continues to occur despite ...
The indications, pharmacokinetics, and therapeutic guidelines for available coagulation products are reviewed. Patients with hemophilia, von Wille-brand's disease (VWD), or acquired inhibitors to ...
Add Yahoo as a preferred source to see more of our stories on Google. Blood clot made of red blood cells, platelets and fibrin protein strands. Thrombus, 3D illustration (Getty Images/iStockphoto) A ...